Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis Diagnosis

ConditionHalitosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Strasbourg, France

About this trial

Halitosis or bad breath is a problem affecting 30% of the world's population. There are many causes, and oral pathologies, including periodontitis, are the main etiology. In order to make a diagnosis, a clinical interview is necessary to distinguish true halitosis from psychological halitosis. In addition, a measurement of volatile sulfur compounds (VSC), the main molecules involved in bad breath, is necessary. This is done during the consultation by measuring the concentration of VSCs in exhaled air. However, few private practices or hospitals have the necessary equipment to measure VSC. As a result, patients are often obliged to travel long distances to obtain a consultation including this specific VSC analysis. The aim of this study is to evaluate the stability of VSC values obtained in gaseous samples up to 7 days after sampling, in order to assess the clinical relevance of analyzing samples at a distance from sampling. The clinical aim is to determine whether self-sampling by the patient at home and extemporaneous analysis could be considered in the diagnosis of halitosis.

Eligibility criteria

Qualifiers

Adult, male or female

Subject affiliated with a social health insurance plan

Able to understand the objectives and risks of the research and to give dated and signed informed consent

Subject presenting for consultation for diagnosis and treatment of periodontal pathology

Disqualifiers

Subject under safeguard of justice

Subject under guardianship or curatorship

Pregnancy or breast-feeding

Impossibility of giving the subject informed information (subject in emergency situation, difficulties in understanding the subject, etc.)

Trial design

Treatments tested in this trial

  • Gaseous sampling:

Treatment groups

No treatment groups listed