The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery. The main question it aims to answer :
-Will there be a difference in the perioperative stress between patients receiving OFA with and without desflurane?
Participants will undergoing sleeve gastrectomy or gastric by pass, will be administered OFA with and without desflurane and blood tests (cortisole, ACTH,dopamine, PRL, adrenaline, noradrenaline, lactate) will be collected perioperatively to compare stress in the two groups.
Signed Informed Consent
ASA II-III
Morbid obesity confirmed diagnosis and approval for surgical treatment
Laparoscopic sleeve gastrectomy (LSG) or Gastric By pass (R-Y By pass /SASI/SADI AND one anastomosis by pass )
Patients declining or withdrawing consent
Patients unsuitabe with regards to compliance to treatment, according to the researcher's assessment
Bradycardia, AV block, , postural hypotension
QTcF>470msec
G.Gennimatas General Hospital
Lead sponsor
National and Kapodistrian University of Athens
Collaborator