Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

In patients with prosthetic valve endocarditis (PVE) and pathological valvular FDG uptake on the initial FDG-PET and not referred to valve replacement at the acute phase, the study will assess whether FDG-PET is able to identify those at increased risk of PVE relapse.

Eligibility criteria

Qualifiers

Patient aged 18 or over;

Have a prosthetic valve implanted surgically or by catheter for at least 3 months;

Presenting a definite IE on a prosthetic valve (ESC definition in force);

Having benefited from an FDG-PET examination for diagnostic purposes as part of the treatment revealing pathological hyperuptake at the level of the prosthetic valve AND carried out <15 days after the start of antibiotic therapy for infective endocarditis;

Disqualifiers

Patient under legal protection, guardianship or curators;

Pregnancy, breastfeeding;

Patient not affiliated to a health insurance scheme or not a beneficiary of a social security scheme;

Simultaneous participation in a study on FDG-PET;

Trial design

Treatments tested in this trial

  • FDG-PET at the end of treatment for IE

Treatment groups

50 Participants
are divided into 1 treatment group