About this trial
The ESPARA study is a multicenter observational research project aiming to monitor, over a three-year period, the evolution of sexual symptoms in male sexual offenders with paraphilia, divided into three groups: receiving antiandrogen treatment, receiving selective serotonin reuptake inhibitors (SSRIs), or no pharmacological treatment. The primary objective is to assess changes in sexual desire intensity and deviant sexual behaviors, while secondary objectives include relapse rates, the role of psychiatric comorbidities, treatment tolerability, and various clinical, cognitive, and life-history factors.
Eligibility criteria
Qualifiers
Men suffering from paraphilias (DSM-5 criteria),
Aged 18 to 65 years,
Sexual offenders (offense or sexual assault including exhibitionism, rape, sexual touching, incest, possession of pedopornographic video material) (severity level 1 to 6 according to WFSBP recommendations),
Subject who has given consent,
Disqualifiers
Subject in prison (regardless of the reason),
Subject under guardianship (patients under legal supervision may, however, be included),
Subjects who have committed a sexual offense and do not meet the DSM-5 criteria for paraphilia."
Trial design
Treatments tested in this trial
- For subjects on SSRIs: bone densitometry