Ex Vivo Evaluation on Human Tissue of the Binding of Experimental Radiolabeled Ligands
ConditionTissue Model
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorCentral Hospital, Nancy, France
About this trial
The HERO project aims to structure an ex vivo screening platform, based on anonymized human tissues, to early assess the tissue fixation of experimental ligands in an ethical, translational approach that complies with the principles of the 3Rs (Replacement, Reduction, Refinement).
Eligibility criteria
Qualifiers
Patients who underwent surgical resection at the Nancy University Hospital after 2019 (Information provided in the welcome booklet or on posters displayed in waiting rooms, mentioning the possible use of data or resection specimens, unless otherwise stated).
No documented objection, in accordance with the MR004 methodology.
Frozen human tissues (slides, blocks, or sections) from surgical resection or biopsy, transmitted by the CRB or the biopathology department.
Samples are fully anonymized before being made available for analysis.
Disqualifiers
• Unusable tissue (degraded, insufficient, contaminated, poorly preserved).
Lack of traceability of the material.
Explicit opposition from the patient to the use of their tissue for research.
Trial design
Treatments tested in this trial
- Early assessment of tissue uptake of experimental ligands
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov