Examine Impact of Topical Application of Active Versus Placebo on the Skin Microbiome in Sensitive Skin.

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age40-60
SponsorAB Biotics, SA

About this trial

The purpose of this study is to build insights to understand how the placebo and active impacts the skin microbiome in women with high skin sensitivity (SS10 \> 13) and sun exposure. Microbiome samples will be taken at baseline after 2 weeks of using the placebo (base without active) as a run-in period followed by the usage of placebo for an additional 4 weeks. The participants will then start the usage of active formula for an additional 8 weeks with microbiome samples collected at the 10-week and 14-week. This will allow us to observe how the microbiome changes over time after the product usage of both placebo and active formulations relative to the pre-regimen condition. In addition, headshot photos will be taken using the Haut AI application at each time point concurrent to the microbiome sample collection to examine changes in skin appearances after the regimen.

Eligibility criteria

Qualifiers

Women aged 40-60 among all ethnicities and Fitzpatrick scale.

With self-assessed sensitive skin (SS10 > 13) and self-reported mild to moderate fine lines and wrinkles.

Must spend minimum 1 hour outside from 10am-4pm at least 5 times per week.

Residing within the same country on the mid to west coast (California, Nevada, Utah, Arizona, Colorado, New Mexico, Kansas, Oklahoma, Texas, Illinois, Kansas, Idaho, Nebraska, Montana).

Disqualifiers

Used any of the products to be tested in the claim study in the past 3 months. - Participation in a similar skin study within the past 30 days.

Have active skin disorders such as psoriasis, eczema, allergies, wounds, scars, or severe acne on their forehead.

Regular use of probiotic supplements

Consumption of fermented foods (including kefir, probiotic containing yoghurt, kombucha or other) for more than 5 times a week

Trial design

Treatments tested in this trial

  • Active Cream
  • Placebo Cream without active substance

Treatment groups

45 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators

AB Biotics, SA

Lead sponsor

Hellobiome

Collaborator

Kaneka Americas Holding Inc.

Collaborator