Exercise and Emotional Learning in Posttraumatic Stress Disorder
ConditionPTSD
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-64
SponsorChristal L Badour
About this trial
The goal of this clinical trial is to test how exercise affects learning and memory processes relevant to the treatment of PTSD. Participants will complete a baseline intake followed by two experimental sessions. During the first experimental session, participants will undergo an MRI session of imaginal exposure to traumatic memory cues followed by 30-minutes of moderate intensity exercise or low intensity exercise. Participants will complete a second session of imaginal exposure with MRI 24 hours later.
Eligibility criteria
Qualifiers
Adults with PTSD related to interpersonal violence
Disqualifiers
Active or recent (within the last 3 months) severe substance use disorder(s)
Active or recent (within the last 3 months) suicidal, psychotic, or manic symptoms/ episodes
Significant developmental disabilities
Current daily benzodiazepine or stimulant use with inability to abstain for study sessions
Trial design
Treatments tested in this trial
- Moderate Intensity Exercise
- Low Intensity Exercise
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Christal L Badour
Lead sponsor
University of Kentucky
Sponsor institution
University of Texas at Austin
Collaborator
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov