About this trial
The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose of this collaborative study involving Denver and Baltimore VAMC sites is to improve health through the detection and rehabilitation management of hospital-acquired weakness in those with CKD. The study goals include identifying and monitoring the optimal muscle assessment sites in clinical settings, examining how muscle health impacts length of hospital stay and physical resilience, and determining how home-based and supervised exercise comparatively addresses post-hospitalization physical resilience using performance tests and Veteran feedback.
Eligibility criteria
Qualifiers
Age > 55 years
Diagnosis of stage 3-4 CKD or an eGFR of <45 mL/min/1.73m2
Disqualifiers
Cardiovascular risk: Poorly controlled hypertension (>160/100)
Coronary event in past 6 months
Class III or IV CHF
symptomatic angina at rest or during exercise
Trial design
Treatments tested in this trial
- Exercise