Exercise and/or HMB in Older Diabetes With Low Muscle Mass
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-80
SponsorWu Shangling
About this trial
The investigators aimed to examine if β-hydroxy-β-methylbutyrate (HMB) supplementation enhances the effects of exercise on muscle mass, physical performance and insulin resistance and observe potential residual effects in older diabetes with low muscle mass, and to find the optimal treatment plan.
Eligibility criteria
Qualifiers
Aged 60-80 ;
Diagnosis of T2DM
Low muscle mass: met a reference value for low muscle mass defined by the Asian Working Group for Sarcopenia (AWGS) criteria with skeletal muscle index <5.7 kg/m2 for women and <7.0 kg/m2 for men
Disqualifiers
Individuals who had an organic disease of the nervous system;
Who were restricted from engaging in exercise by a medical doctor;
Who was unconscious and unable to complete the questionnaire;
Who used other supplementations for muscle mass gain;
Trial design
Treatments tested in this trial
- HMB
- Exercise
- Placebo
- Education
Treatment groups
120 Participants
are divided into 4 treatment groupsLocations
Sponsors and collaborators
Wu Shangling
Lead sponsor
First Affiliated Hospital, Sun Yat-Sen University
Sponsor institution
Source ClinicalTrials.gov