Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorSunnybrook Health Sciences Centre
About this trial
People with vascular conditions are at risk of having memory problems, and these memory problems increase the risk for further cognitive decline. Brain stimulation has been used to improve mood and memory. Transcranial direct current stimulation (tDCS) is believed to work best on brain cells that are active or "primed" before stimulation. The purpose of this study is to compare the effects of exercise and tDCS on memory performance in patients who have completed cardiac rehabilitation and are at risk of cognitive decline.
Eligibility criteria
Qualifiers
≥50 years of age; females must be post-menopausal
Presence of cerebrovascular and/or cardiovascular risk factors or coronary artery disease
Montreal Cognitive Assessment (MoCA) <27
Sufficiently proficient in English
Disqualifiers
History of stroke
Change in psychotropics within the last 4 weeks
Current benzodiazepine use due
Metal implants that would preclude safe use of tDCS or neuroimaging
Trial design
Treatments tested in this trial
- tDCS
- Exercise
- Sham stimulation
- Treatment as usual
Treatment groups
64 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov