EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

ConditionParoxysmal Atrial Fibrillation

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorVirginia Commonwealth University

About this trial

Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).

Eligibility criteria

Qualifiers

Age ≥18 years

Diagnosis of paroxysmal AF

Left ventricular ejection fraction ≥50%

Scheduled for catheter ablation

Disqualifiers

Persistent or permanent AF

Prior ablation (catheter based or surgical) for AF

Significant sinus node dysfunction

Implanted pacemaker or defibrillator

Trial design

Treatments tested in this trial

Self- Report Evaluation-Duke Activity Status Index
Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire
Cardiopulmonary exercise test (CPET)
Transthoracic echocardiogram
Ambulatory cardiac rhythm assessment
Cardiovascular magnetic resonance (CMR)

Treatment groups

50 Participants

are divided into 1 treatment group

Sponsors and collaborators

Virginia Commonwealth University

Lead sponsor

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Source ClinicalTrials.gov