Exercise in Patients With Hypermobile Joints and Knee Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorUniversity of Southern Denmark
About this trial
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving activity-related pain in young patients (18-45 years) with hypermobile joints and knee pain.
Eligibility criteria
Qualifiers
Persistent knee pain for ≥ 3 months (self-reported)
Knee pain ≥ 30mm during the last week using a 0-100 mm visual analogue scale (VAS; 0=no pain and 100=worst imaginable pain) (self-reported)
Generalised joint hypermobility assessed with the Five-Part Hypermobility Questionnaire (positive ≥ 2/5) (self-reported)
Local knee joint hypermobility using the passive hyperextension of the knee in standing (positive > 10 degrees of hyperextension) and confirmed in supine lying (heel resting on 20 cm high block on the bench surface), with passive knee hyperextension (positive > 10 degrees) (objectively measured)
Disqualifiers
Diagnosed with patellar tendinopathy
Pregnancy or childbirth within the past year (due to increased levels of relaxin that could affect joint stability)
Knee surgery within the past year
Participation in regular structured resistance training within the past six months
Trial design
Treatments tested in this trial
- Neuromuscular training for the knee
- High-load strength training for the knee
Treatment groups
90 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Southern Denmark
Lead sponsor
Independent Research Fund Denmark
Collaborator
Odense Patient Data Explorative Network
Collaborator
Source ClinicalTrials.gov