Exercise, Insulin Resistance, and Chronic Pain in Postmenopausal Women.
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeNot listed
SponsorSão Paulo State University
About this trial
This study aims to investigate the effects of a combined exercise program on chronic pain in postmenopausal women, considering insulin resistance as a potential physiological mediator. The intervention will assess changes in pain intensity, metabolic and inflammatory biomarkers, psychosocial factors, and body composition. The findings may contribute to understanding the metabolic mechanisms underlying chronic pain in postmenopausal women and support exercise as a non-pharmacological therapeutic strategy.
Eligibility criteria
Qualifiers
Postmenopausal women, defined as between 12 months and 5 years since the last menstrual period.
Not using hormone replacement therapy.
Not engaged in regular physical exercise (defined as more than once per week in the last months).
With or without insulin resistance.
Disqualifiers
Diagnosis of neurological diseases (e.g., Parkinson's disease, multiple sclerosis, or stroke sequelae).
Severe psychiatric disorders.
Inflammatory autoimmune diseases (e.g., rheumatoid arthritis or systemic lupus erythematosus).
Active neoplasms.
Trial design
Treatments tested in this trial
- Combined Exercise Program
- Usual Care Group
Treatment groups
50 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov