Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Medical Center Groningen
About this trial
To aim of the EXPOSURE study is to investigate the effects of epicardial fat on cardiac function, pericardial constraint and pulmonary artery vasodilatation using cardiac magnetic resonance (CMR) imaging at rest and during exercise stress testing in patients with HFpEF.
Eligibility criteria
Qualifiers
Signs and symptoms of HF according to the Europeans Society of Cardiology guideline.
LV ejection fraction ≥40%.
HFA-PEFF score ≥5 or HFA-PEFF score 2-4 in combination with positive stress test (Figure 1).
>18 years of age
Disqualifiers
Body weight >140 kg
Atrial fibrillation or other significant arrhythmia during the assessment
Contraindications for CMR (e.g. claustrophobia, implanted cardiac devices)
Myocardial infarction, percutaneous coronary intervention or coronary artery bypass graft <3 months or untreated severe obstructive coronary artery stenosis
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov