Exercise Response in Humans With Obesity

ConditionObese
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-45
SponsorMayo Clinic

About this trial

This study is being done to understand how chronic inflammation affects muscle function and responses to exercise.

Eligibility criteria

Qualifiers

Obese men and women ≥ 20 and ≤ 45 years of age.

Disqualifiers

Diabetes or fasting plasma glucose >126 mg/dL

Anemia (female subjects hemoglobin of <11 g/dl and male subjects hemoglobin <12 g/dl)

Active coronary artery disease or history of unstable macrovascular disease (unstable angina, myocardial infarction, stroke, and revascularization of coronary, peripheral or carotid artery within 3 months of recruitment)

Renal failure (serum creatinine > 1.5mg/dl)

Trial design

Treatments tested in this trial

  • Treadmill Test
  • Strength Test
  • Dual-Energy X-Ray Absorptiometry
  • Muscle Biopsy
  • Fat Biopsy
  • Resting Energy Expenditure
  • Magnetic resonance imaging

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators