About this trial
To investigate the effects of simple dietary management and diet combined with exercise capacity-targeted intelligent lifestyle management on improving metabolic indicators in patients with overweight/obesity and metabolic syndrome.
Eligibility criteria
Qualifiers
Aged between 20 and 60 years.
Overweight or obese, with a Body Mass Index (BMI) ≥ 24 kg/m² and < 40 kg/m².
Central obesity: Waist circumference ≥ 90 cm for males or ≥ 85 cm for females.
Hyperglycemia: Fasting plasma glucose (FPG) ≥ 6.1 mmol/L, or 2-hour plasma glucose ≥ 7.8 mmol/L during an oral glucose tolerance test (OGTT), and/or currently receiving treatment for previously diagnosed diabetes.
Disqualifiers
History of cardiovascular or cerebrovascular disease, or in the acute phase, including: angina pectoris, myocardial infarction, coronary revascularization surgery, stroke (ischemic or hemorrhagic, including transient ischemic attack), symptomatic peripheral artery disease requiring surgery or diagnosed via angiographic techniques, ventricular arrhythmias, uncontrolled atrial fibrillation, congestive heart failure (New York Heart Association class III or IV), hypertrophic cardiomyopathy, history of aneurysm with diameter ≥ 5.5 cm, or history of aneurysm surgery.
Malignancy or history of malignancy within the past five years.
Religious restrictions or dysphagia preventing adherence to the recommended diet.
Contraindications to exercise, such as orthopedic disorders.
Trial design
Treatments tested in this trial
- Dietary Prescription
- Personalized Exercise Prescription
- Metabolic Syndrome Prevention and Education