About this trial
This interventional crossover study examines the effect of exercise timing relative to meal intake on postprandial glucose responses in healthy, physically active young adults. Participants complete five experimental conditions involving endurance exercise performed before or after breakfast or dinner, as well as a non-exercise control condition, while wearing a continuous glucose monitoring device.
Postprandial glucose responses are assessed for the three consecutive meals following each exercise session. Following morning exercise, outcomes are assessed after breakfast, lunch, and dinner on the same day. Following evening exercise, outcomes are assessed after dinner on the same day and after breakfast and lunch on the subsequent day. All meals are standardized and consumed at fixed clock times.
Eligibility criteria
Qualifiers
Age 18 to 35 years
Body mass index 18.5 to 24.9 kg per square meter
Able to complete 45 minutes of continuous running at an intensity corresponding to 75 to 85 percent of maximal heart rate without stopping
Engages in regular endurance-type physical activity
Disqualifiers
Acute or chronic illness
Metabolic disorders or conditions associated with altered glucose or lipid metabolism
Use of medications known to interfere with glucose metabolism or study outcomes
Intolerance or allergy to components of the standardized study diets
Trial design
Treatments tested in this trial
- Timed Endurance Exercise
- No Exercise Control