About this trial
This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.
Eligibility criteria
Qualifiers
Persons with mild-moderate idiopathic Parkinson's Disease (Modified Hoehn & Yahr Scale stages 0.5-3.5);
On a stable dosage of medication during the previous month;
Having poor sleep quality defined as a score > 15 in the PDSS-2 and/or reporting subjective sleep complaints affecting their sleep quality;
Disqualifiers
Having atypical parkinsonism, dementia, stroke, or any other neurological condition;
Presenting severe untreated obstructive sleep apnea (OSA);
Having a Montreal Cognitive Assessment (MoCA) score <18
Having a Beck Depression Inventory score >31;
Trial design
Treatments tested in this trial
- Cardiovascular training (CT)
- Resistance training (RT)
- Multimodal training (MT)
Treatment groups
Sponsors and collaborators
McGill University
Lead sponsor
Jewish Rehabilitation Hospital
Collaborator
The Memory Lab
Collaborator
The Human Brain Control of Locomotion Lab (HBCL)
Collaborator
The Cummings Centre
Collaborator
Canadian Institutes of Health Research (CIHR)
Collaborator