Exercise Training for People With Advanced Multiple Sclerosis
ConditionMultiple Sclerosis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Ottawa
About this trial
The goal of this interventional study is to test the feasibility of 12 weeks of aerobic exercise for people with advanced multiple sclerosis (i.e., wheelchair users). The main questions it aims to answer are:
* Is the exercise intervention feasible in terms of study processes, resources, management, safety, and acceptability? * Can the intervention improve aerobic fitness, function in daily life, cognition, symptoms of fatigue and pain, and sensation? * What are participants' experiences of taking part in the exercise intervention?
Participants will take part in moderate-intensity aerobic exercise twice a week for 12 weeks in a supervised research setting. Outcomes will be measured at baseline (0 weeks), mid-intervention (6 weeks), post-intervention (12 weeks), and 12-weeks after the intervention (24 weeks). The outcomes include feasibility measures, aerobic fitness, function in daily life, cognition, symptoms of fatigue and pain, sensation, and participant experiences of taking part in the exercise intervention.
Eligibility criteria
Qualifiers
≥18 years of age
Self-reported diagnosis of MS
Expanded Disability Status Score ≥ 7.0
Stable course of disease-modifying therapy over past six months
Disqualifiers
Diagnosis of other neurological conditions
Relapse within 30 days
Signs or symptoms of acute or uncontrolled cardiovascular, renal or metabolic disease or other conditions that make it unsafe to exercise
Currently engaging in regular aerobic exercise (≥ 2 sessions/week for ≥ 12 weeks)
Trial design
Treatments tested in this trial
- Aerobic Exercise Training
Treatment groups
12 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
University of Ottawa
Lead sponsor
Multiple Sclerosis Society of Canada
Collaborator
Source ClinicalTrials.gov