Peanut allergy is the most common cause of fatal and near-fatal food-allergic reactions and egg allergy is among the two most common causes of food-induced anaphylaxis. The proposed research will explore the development of sensitization to these food(s) in infants based on maternal consumption or avoidance during pregnancy and breastfeeding.
English-speaking adults, 18 years or older. (Spanish speaking adults may be included after consent document is translated and Spanish speaking study representatives are available to conduct and answer questions during informed consent process and for study follow up.)
Maternal consent must be provided for infants.
Pregnant women from the time pregnancy is confirmed until 27 weeks of gestation.
no chronic inflammatory conditions that require long-term systemic immunosuppressive medications in first or second trimester
Inability or unwillingness of subject to give written informed consent or comply with study protocol.
Known history of renal/liver/cardiac insufficiency in the mother or infant.
Pregnant women with PN or egg allergy.
Pregnant women who refuse to eat PN (or peanut products) and/or eggs.
University of Rochester
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator