Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity

ConditionPain, Acute
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorKristian Kjær Petersen

About this trial

This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities. The study aims to:

A) Examine how experimental muscle pain in different types of muscles (ankle plantar-flexion, knee extension, and flexion muscles) affects kinematics, kinetics, and muscle activation

Participants will receive six muscle injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition) in 1) m. gastrocnemius, 2) m. semitendinosus, and 3) m. biceps femoris.

Eligibility criteria

Qualifiers

Healthy men and women aged 18-45 years

Disqualifiers

Pregnancy

Drug addiction, defined as the use of cannabis, opioids, or other drugs

Previous or current neurologic or musculoskeletal illnesses

Current pain

Trial design

Treatments tested in this trial

  • Hypertonic saline injection
  • Isotonic saline injection

Treatment groups

36 Participants
are divided into 6 treatment groups

6

Treatment groups

See each treatment group below.

Sponsors and collaborators

Kristian Kjær Petersen

Lead sponsor

Aalborg University

Sponsor institution