Exploratory Study of EBV DNA Titre Clearance Whilst on Proton Beam Therapy

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age8-30
SponsorThe Christie NHS Foundation Trust

About this trial

How does plasma Epstein-Barr Virus (EBV) DNA level change during definitive radiation therapy for nasopharyngeal carcinoma (NPC) in the teenage and young adult cohort and does it correlate with outcomes?

Eligibility criteria

Qualifiers

Children and young adults (8-30 years old)

Pathologically confirmed EBV-positive nasopharyngeal carcinoma

Stage I-IVA (AJCC 8th Edition)

Planned to commence curative-intent radiation therapy

Disqualifiers

Recurrent NPC

Concurrent or previously treated EBV-associated malignancy

Prior radiation therapy

Contraindications to MRI

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Locations

This trial has no locations