About this trial
Exploring the therapeutic efficacy of Theta Burst Stimulation (TBS) over the right inferior frontal gyrus (RIFG) in autism, including changes in core symptoms, adaptive functioning, neuropsychological performance, and neurophysiological signals.
Eligibility criteria
Qualifiers
Participants aged 8 to 30 years with a clinical diagnosis of Autism Spectrum Disorder (ASD), confirmed by the ADOS-2 (Autism Diagnostic Observation Schedule, Second Edition).
DSM-5 severity level of ASD: level 1 or level 2
Participants who have been on a stable treatment regimen prior to the study, or those for whom conventional treatments have been assessed as ineffective by a physician, or those who decline conventional treatment.
A score of ≥ 15 on the University of California Brief Assessment of Capacity to Consent (UBACC) and demonstrated understanding of study aims and risks via the teach-back method.
Disqualifiers
Previous or current severe neurological disorders, especially epilepsy, visual or auditory impairments
Previous or current severe systemic diseases such as cardiovascular disease, diabetes or hypertension
Previous or current severe brain injury
Implementation of metal materials such as a pacemaker or medication pump
Trial design
Treatments tested in this trial
- intermittent theta burst stimulation