Exploring the Correlations of Lung Ultrasound with Delirium and Outcomes in Acute GEriatrics World: a Multicenter, Prospective, Observational Study from the GRETA Group of the Italian Society of Gerontology and Geriatrics

ConditionsAcute Respiratory Failure Delirium in Old Age Pneumonia Acute Heart Failure (AHF)Chronic Obstructive Pulmonary Disease (COPD)Ultrasound Exams

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age65+

SponsorUniversity of Milano Bicocca

About this trial

The purpose of this observational study is to investigate the prognostic relevance of lung ultrasound (LUS) performed on older patients (aged 65 and above) admitted to the hospital with acute respiratory symptoms. The primary objective is to determine if LUS-detected pulmonary abnormalities upon hospital admission are associated with the development of delirium during hospitalization. Secondary objectives include assessing the association between LUS patterns and clinical outcomes such as oxygen supplementation duration, non-invasive ventilation use, mortality, and length of hospital stay. This study involves no interventions and will monitor patients using LUS as part of their regular clinical care in multiple centers.

Eligibility criteria

Qualifiers

Patients aged 65 years or older, admitted directly from the Emergency Room or Emergency Medical Services with acute respiratory symptoms or signs.

Dyspnea or cough.

Oxygen saturation less than 94% or respiratory rate ≥ 22 breaths per minute, or PaO2/FiO2 < 300.

Clinical suspicion of acute respiratory illness (e.g., pneumonia, acute congestive heart failure, pulmonary edema, COPD, pleural effusion, pneumothorax).

Disqualifiers

Presence of delirium upon admission.

Refusal to sign the informed consent form or consent to data collection.

Terminal illness with an estimated survival prognosis of no more than 3 months.

Previous open thoracic or cardiothoracic surgery compromising the quality of LUS images.

Trial design

Treatments tested in this trial

Not listed

Trial groups

480 Participants

are grouped into 2 trial groups

Sponsors and collaborators

University of Milano Bicocca

Lead sponsor

Source ClinicalTrials.gov