Exploring the Influence of Glucagon-like Peptide -1 (GLP-1) Medications on Food Cravings, Food Selection, and Food Intake Following Exposure to Food Advertisements

ConditionGLP - 1
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorPenn State University

About this trial

The purpose of this randomized control trial is to compare how food cravings, food selection, and food consumption change in response to frequent food advertisements compared to non-food advertisements in adults taking GLP-1 (weight loss) medications. The primary question we aim to answer is: do GLP-1 medications reduce an individual's vulnerability to external triggers that drive food cravings and consumption?

Participants will:

* report daily food consumption for a total of 10 days, * receive eight daily prompts to view food or non-food related advertisements, and respond to a short 9-question survey for 7 days, * answer several questionnaires, * and complete two in-person visits to complete a virtual reality food selection task.

Eligibility criteria

Qualifiers

Adults (18+) with overweight or obesity (BMI >25 kg/m2)

On an injectable form of tirzepatide GLP-1 medication at a minimum dose of 7.5 mg, taking it as prescribed by their doctor

Not currently taking an incretin-based medication at baseline other than the GLP-1 medication

Fluent in English

Disqualifiers

Do not have consistent access to a smart phone that can access the study software

Diagnosed with cognitive or physical disability or epilepsy

Adults taking a compound GLP-1

Trial design

Treatments tested in this trial

  • Food advertisements
  • Tech advertisements

Treatment groups

50 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Penn State University

Lead sponsor

Penn State Health

Collaborator