Exploring the Mechanisms of Postoperative Delirium in Cirrhotic Patients Through Multi-Omics Integrative Analysis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorSichuan Provincial People's Hospital

About this trial

This study looks at memory problems after surgery in people with liver disease. We want to know how often these problems happen and what might cause them. The main question it aims to answer is:

1. Do people with liver disease have more memory problems after stomach surgery than people without liver disease? If yes, how much more often? 2. Are changes in stomach bacteria and body chemicals related to these memory problems?

Who can join:

* Adults getting stomach surgery * Both people with and without liver disease

What participants will do:

* Take memory tests before and after surgery * Give stool (poop) and blood samples before and after surgery

Why this matters:

Memory problems after surgery can make recovery harder. If we find that stomach bacteria or body chemicals are involved, doctors might find new ways to prevent these problems in people with liver disease.

Eligibility criteria

Qualifiers

Age: 18-80 years

Patients with or without liver cirrhosis scheduled for upper abdominal surgery due to various clinical indications

Ability to comply with the study protocol and provide informed consent

Disqualifiers

Comorbid severe cardiac, pulmonary, or renal diseases

Psychiatric disorders

Inability to communicate clearly

Any condition preventing effective communication or cooperation

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

133 Participants
are grouped into 2 trial groups

Locations

This trial has no locations