Exposure to Organochlorine Pollutants and Impact on Development in the Peripubertal Age in Guadeloupe

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-22
SponsorCentre Hospitalier Universitaire de la Guadeloupe

About this trial

In the context of environmental pollution of the French West Indies by chlordecone and questions about health consequences, monitoring at the peripubertal age of children born alive in the TIMOUN cohort is justified in several respects: - existence of an already established mother-child cohort whose live-born children will reach peripubertal ages during the period 2020-2022; - opportunity to verify hypotheses put forward on the basis of toxicological data acquired in laboratory animals and the hormonal characteristics of chlordecone (endocrine disruptor); - strong societal demand for such research to be carried out because of concerns about the sensitivity of children and adolescents to the effects of environmental xenobiotics, in particular on sexual development and the age of puberty; - recommendation of the Scientific Council Chlordecone Inserm - InVS; specific action of the National Plan Chlordecone IV.

Eligibility criteria

Qualifiers

Be born to a mother whose pregnancy was included in the Timoun cohort (2004 - 2007) and whose parents agreed to be contacted later.

Residing in Guadeloupe at the peripubertal age

Affiliation to a social security scheme

Agreement to participate in the study and informed consent signed by the minor

Disqualifiers

Refusal to participate in the research

Trial design

Treatments tested in this trial

  • Clinical examination

Treatment groups

650 Participants
are divided into 1 treatment group

Sponsors and collaborators

Centre Hospitalier Universitaire de la Guadeloupe

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Collaborator