Expression of SLC25A48 in Chronic Obstructive Pulmonary Disease
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorFu Jen Catholic University
This study aims to investigate the expression level of SLC25A48, a mitochondrial choline transporter, in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease, and to analyze its correlation with inflammatory markers and choline metabolic byproducts.
pre-COPD or COPD stages I-IV as per the 2023 GOLD guidelines (case group)
healthy individuals without chronic diseases or major medical conditions
diagnosed with neuromuscular diseases
experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months
assessed by a physician to have severe malnutrition or a significantly low BMI
continuously taking folic acid supplements