Extremely Preterm Respiratory Outcome Cohort

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 7
SponsorSeoul National University Hospital

About this trial

This study examines the respiratory outcomes of preterm infants born at gestational ages less than 29 weeks, spanning from birth to 24 months corrected age. It delves into the intricacies of respiratory function impairment attributable to diverse factors, such as respiratory distress syndrome, bronchopulmonary dysplasia, postnatal corticosteroids, ventilatory support, as well as nutritional aspect during NICU stay. Furthermore, it scrutinizes the incidence of chronic respiratory diseases stemming from these conditions, assessing their long-term impact on respiratory prognosis post-discharge. In addition to respiratory aspects, the research extends its focus to the growth and developmental outcomes of preterm infants. By synthesizing these multifaceted elements, the study aspires to enhance current treatments and preventative measures for respiratory conditions in preterm infants.

Eligibility criteria

Qualifiers

Infants born at gestational age less than 29 weeks with cohort consent obtained within 7 days of birth

Disqualifiers

death within 3 days of birth

severe structural heart defects

structural abnormalities in the upper airway, lungs, or chest

congenital anomalies that may impact cardiopulmonary function

Trial design

Treatments tested in this trial

  • Standard care for preterm infants

Treatment groups

600 Participants
are divided into 1 treatment group

Sponsors and collaborators

Seoul National University Hospital

Lead sponsor

Asan Medical Center

Collaborator

Samsung Medical Center

Collaborator

Seoul National University Bundang Hospital

Collaborator

Chonnam National University Hospital

Collaborator

Severance Hospital, Yonsei University College of Medicine

Collaborator

Ajou University Medical Center

Collaborator