Fabry Cardiomyopathy: Identification of Early Myocardial Structural and Tissue Abnormalities Using Multiparametric MRI

ConditionFabry Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Health Network, Toronto

About this trial

This study will evaluate whether cardiac MRI T1 and T2 mapping improves our ability to detect early abnormalities in the heart in patients with Fabry disease and identify patients at increase risk of adverse events.

Eligibility criteria

Qualifiers

Fabry disease;

Age ≥ 18 years.

Disqualifiers

History of myocardial infarction;

Contraindication to MRI.

Trial design

Treatments tested in this trial

  • Cardiac MRI, ECG/Holter and Blood Biomarkers

Treatment groups

300 Participants
are divided into 1 treatment group

Sponsors and collaborators

University Health Network, Toronto

Lead sponsor

Vancouver General Hospital

Collaborator

The Cleveland Clinic

Collaborator

Icahn School of Medicine at Mount Sinai

Collaborator

IRCCS Policlinico S. Donato

Collaborator

Alberta Health services

Collaborator

Libin Cardiovascular Institute of Alberta

Collaborator

Vancouver Coastal Health

Collaborator