Factors for the Onset and Course of Axial Spondylitis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKarolinska Institutet

About this trial

In a research project, investigators want to study the course of the disease of axial spondylitis: the causes of disease onset, prognosis, and treatment effects. The goal is to improve treatment and in the long run also prevention of the disease. The project has a focus on the body\'s own substance prostaglandin, and its proinflammatory role in spondylitis, but also other substances may be analyzed in blood and urine samples.

The purpose of the research project is include newly diagnosed treatment-naive patients with axial spondyloarthritis, to follow them after 1 and 2 years after treatment start, to collect clinical data, questionnaires, blood and urinsamples to find blood or urine markers that can be used for precision therapy of axial spondylitis.

Eligibility criteria

Qualifiers

newly diagnosed patients with axial spondyloarthritis

treatment-naive

18 years of age or older

Swedish-speaking

Disqualifiers

DMARD treatment,

ongoing infection

ongoing malignancy

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

1,000 Participants
are grouped into 1 trial group

Sponsors and collaborators

Karolinska Institutet

Lead sponsor

Karolinska University Hospital

Collaborator