Factors in Learning And Plasticity: Macular Degeneration

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-89
SponsorUniversity of Alabama at Birmingham

About this trial

A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging population are consistent with the mission of the NIA.

Eligibility criteria

Qualifiers

Aged 18-89

Severely impaired vision in both eyes (20/100 or worse)

diagnosis of Macular Degeneration by an Ophthalmologist

Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (MAIA)

Disqualifiers

Pacemaker or any ferromagnetic metal implanted in their body

Metal of any type implanted in their head (limited dental work is acceptable)

Claustrophobia

Being hearing-impaired

Trial design

Treatments tested in this trial

  • Training visual sensitivity
  • Combination training

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Alabama at Birmingham

Lead sponsor

University of California, Riverside

Collaborator