About this trial
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging population are consistent with the mission of the NIA.
Eligibility criteria
Qualifiers
Aged 18-89
Severely impaired vision in both eyes (20/100 or worse)
diagnosis of Macular Degeneration by an Ophthalmologist
Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (MAIA)
Disqualifiers
Pacemaker or any ferromagnetic metal implanted in their body
Metal of any type implanted in their head (limited dental work is acceptable)
Claustrophobia
Being hearing-impaired
Trial design
Treatments tested in this trial
- Training visual sensitivity
- Combination training
Treatment groups
Sponsors and collaborators
University of Alabama at Birmingham
Lead sponsor
University of California, Riverside
Collaborator