Fasted Exercise Training in Type 1 Diabetes (FED-T1D)
ConditionDiabetes Mellitus, Type 1
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorUniversity of Alberta
About this trial
This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to similar training performed after breakfast in people with type 1 diabetes. Training will take place over 12 weeks.
Eligibility criteria
Qualifiers
Clinical diagnosis of type 1 diabetes for 5 or more years.
Treatment using an insulin pump with no change in treatment modality for > 2 continuous months and willing to share CGM data with the research team. Insulin delivery can be managed using either manual open-loop system (non-AID) or a hybrid closed loop (AID) systems.
Using rapid (e.g., Aspart, Lispro or Glulisine) or ultra-rapid (e.g., FiAsp) acting insulin analogs.
HbA1c 7.0-9.9%.
Disqualifiers
Major complication within the previous 3 months (e.g., severe hypoglycemia requiring assistance, diabetic ketoacidosis, or cardiovascular event).
Restriction in aerobic or resistance exercise due to significant diabetes complications (e.g., severe peripheral neuropathy, active proliferative retinopathy, etc.) or other type of limitations (e.g., orthopedic, severe arthritis, etc.).
Uncontrolled hypertension (e.g., blood pressure >160 mmHg systolic or >100 mmHg diastolic).
Implanted device, material, or having a condition contraindicated to MRI.
Trial design
Treatments tested in this trial
- Fasted Exercise
- Postprandial Exercise
Treatment groups
20 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Alberta
Lead sponsor
Alberta Diabetes Institute
Collaborator
Source ClinicalTrials.gov