FDG PET/MR Imaging of Peripheral Pain Generators
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorUniversity of Wisconsin, Madison
About this trial
The purpose of this research is to determine if a PET/MRI scan using FDG can accurately identify the source of chronic pain. Identifying the source of pain may help doctors treat chronic pain more effectively. Approximately 128 participants will be enrolled and can expect to be on study for up to 12 months.
Eligibility criteria
Qualifiers
18-85 years old
Presents with persistent pain with pain score of ≥4 on Numerical Rating Scale [0:10] for at least 6 months following joint arthroplasty or arthroscopy.
Able and willing to provide informed consent
Willing and able to undergo PET/MRI (arthroplasty and arthroscopy participants) and PET/CT (arthroplasty participants only)
Disqualifiers
Inability to understand and communicate with the investigators to complete the study-related questionnaires.
Any co-morbidity which results in severe systemic disease limiting function as defined by the American Society of Anesthesiology (ASA) physical status classification > 3, such as the presence of current or past (6 months) pulmonary, hepatic, renal disease, arthritis, hematopoietic, and neurological diseases not related to chronic pain.
Pregnant or breastfeeding. (Individuals with childbearing potential will be asked to verbally confirm they are not pregnant. If they cannot confirm, they will have a urine pregnancy test either at the imaging study visit or within 7 days prior to the imaging study visit.)
Subject with contraindication(s) to or inability to undergo PET/MRI
Trial design
Treatments tested in this trial
- FDG radiotracer
- PET/MRI
- PET/CT imaging
Treatment groups
128 Participants
are divided into 4 treatment groupsSponsors and collaborators
University of Wisconsin, Madison
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborator
Arthroscopy Association of North America (AANA)
Collaborator
Source ClinicalTrials.gov