Feasibility and Acceptability of an Intervention to Support People With Severe Mental Illness in South Africa

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of KwaZulu

About this trial

Despite commendable progress in developing mental health systems in low-and-middle income countries, critical gaps remain, particularly the development of community-based systems of support for people living with severe mental illness (SMIs). This application will pilot a co-developed health system strengthening intervention programme in a South African district in order to determine its feasibility, appropriateness and limited efficacy in reducing readmission following discharge from acute psychiatric hospitalization. By generating preliminary data on the real-world implementation of a co-developed programme in low-resource contexts in South Africa, this application seeks to build on an existing foundation of research partnerships and local government collaboration to develop a transitional support intervention that could yield significant and tangible impacts on people living with SMIs in low-resource communities.

Eligibility criteria

Qualifiers

Adults (aged 18 years and above);

F20-29 including schizophrenia, delusional disorders, schizotypal disorders, acute polymorph psychotic disorders, schizoaffective disorders

F30-39 Mood [affective] disorders with psychoses

F30.2 Mania with psychotic symptoms

Disqualifiers

Under 18 years of age

Active suicidal ideation

Substance abuse or dependence as primary diagnosed psychiatric condition

Personality disorders

Trial design

Treatments tested in this trial

  • Multilevel psychosocial support for people living with severe mental illness and their caregivers

Treatment groups

86 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of KwaZulu

Lead sponsor

Columbia University

Collaborator

Universiteit Antwerpen

Collaborator

Medical Research Council, South Africa

Collaborator