About this trial
Despite commendable progress in developing mental health systems in low-and-middle income countries, critical gaps remain, particularly the development of community-based systems of support for people living with severe mental illness (SMIs). This application will pilot a co-developed health system strengthening intervention programme in a South African district in order to determine its feasibility, appropriateness and limited efficacy in reducing readmission following discharge from acute psychiatric hospitalization. By generating preliminary data on the real-world implementation of a co-developed programme in low-resource contexts in South Africa, this application seeks to build on an existing foundation of research partnerships and local government collaboration to develop a transitional support intervention that could yield significant and tangible impacts on people living with SMIs in low-resource communities.
Eligibility criteria
Qualifiers
Adults (aged 18 years and above);
F20-29 including schizophrenia, delusional disorders, schizotypal disorders, acute polymorph psychotic disorders, schizoaffective disorders
F30-39 Mood [affective] disorders with psychoses
F30.2 Mania with psychotic symptoms
Disqualifiers
Under 18 years of age
Active suicidal ideation
Substance abuse or dependence as primary diagnosed psychiatric condition
Personality disorders
Trial design
Treatments tested in this trial
- Multilevel psychosocial support for people living with severe mental illness and their caregivers
Treatment groups
Sponsors and collaborators
University of KwaZulu
Lead sponsor
Columbia University
Collaborator
Universiteit Antwerpen
Collaborator
Medical Research Council, South Africa
Collaborator