About this trial
The goal of this clinical trial is to learn whether a camera pill examination of the whole bowel can be used to diagnose Crohn's disease instead of colonoscopy and a small bowel examination (either MRI or camera pill) in patients aged 18-40 years suspected of having Crohn's disease.
The main question it aims to answer is:
How many patients examined with a camera pill examination of the whole bowel will have a complete examination of the whole bowel and have a diagnosis made without need for any more examinations?
Researchers will compare with patients examined with colonoscopy and a small bowel examination.
Participants will:
* Be examined with either a camera pill examination of the whole bowel, or a colonoscopy and a small bowel examination * Have their electronic medical records checked to see if a diagnosis has been made * Have an interview every three months if diagnosed with an inflammatory bowel disease or after a year if no disease was found
Eligibility criteria
Qualifiers
Clinical suspicion of CD*
Age 18-40 years
Signed informed consent
Diarrhea and/or abdominal pain for more than 1 month (or repeated episodes of diarrhea and/or abdominal pain) and either
Disqualifiers
Previous intestinal resection
Positive serologic markers for celiac disease
Positive stool polymerase chain reaction for pathogenic bacteria
Positive stool polymerase chain reaction for intestinal parasites
Trial design
Treatments tested in this trial
- Panenteric capsule endoscopy
- Ileocolonoscopy
- MRI enterography
- Small bowel capsule endoscopy
Treatment groups
Sponsors and collaborators
Esbjerg Hospital - University Hospital of Southern Denmark
Lead sponsor
Odense University Hospital
Collaborator
Svendborg Hospital
Collaborator
Skane University Hospital
Collaborator
Vejle Hospital
Collaborator