About this trial
This study tests out procedures to look at whether a type of brain stimulation called transcranial magnetic stimulation impacts flexible shifts in behavior in obsessive-compulsive disorder (OCD). This study examines whether study procedures are feasible and acceptable to people participating in the study, but does not determine whether this type of brain stimulation causes changes.
Eligibility criteria
Qualifiers
Current primary DSM-5 OCD diagnosis and current Y-BOCS total score of ≥16 (OCD group, only) or no current diagnosis of an emotional disorder, and no known history of OCD, PTSD, anxiety disorder(s), or recurrent major depressive disorder (Healthy participant group, only)
18-60 years of age
ability to speak, read, write, and understand English sufficiently well to complete study procedures and provide informed consent
psychotherapy and/or psychiatric medication use remain stable for 6 weeks prior to study entry
Disqualifiers
Presence of current psychiatric diagnosis (healthy control group, only)
active substance use disorder
history of mania or hypomania, or lifetime presence of significant psychotic symptoms
active suicidal or homicidal ideation
Trial design
Treatments tested in this trial
- continuous theta-burst transcranial magnetic stimulation (cTBS)