Feasibility of Modulating Cognitive Control in OCD

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorDartmouth-Hitchcock Medical Center

About this trial

This study tests out procedures to look at whether a type of brain stimulation called transcranial magnetic stimulation impacts flexible shifts in behavior in obsessive-compulsive disorder (OCD). This study examines whether study procedures are feasible and acceptable to people participating in the study, but does not determine whether this type of brain stimulation causes changes.

Eligibility criteria

Qualifiers

Current primary DSM-5 OCD diagnosis and current Y-BOCS total score of ≥16 (OCD group, only) or no current diagnosis of an emotional disorder, and no known history of OCD, PTSD, anxiety disorder(s), or recurrent major depressive disorder (Healthy participant group, only)

18-60 years of age

ability to speak, read, write, and understand English sufficiently well to complete study procedures and provide informed consent

psychotherapy and/or psychiatric medication use remain stable for 6 weeks prior to study entry

Disqualifiers

Presence of current psychiatric diagnosis (healthy control group, only)

active substance use disorder

history of mania or hypomania, or lifetime presence of significant psychotic symptoms

active suicidal or homicidal ideation

Trial design

Treatments tested in this trial

  • continuous theta-burst transcranial magnetic stimulation (cTBS)

Treatment groups

12 Participants
are divided into 2 treatment groups

Locations

This trial has no locations