Cardiac resynchronization therapy（CRT） benefits a portion of patients, while more patients are not yet indicated to a therapy that mechanically helps the heart systole and/or diastole. Synchronized diaphragmatic pacing may be feasible to induce diaphragm local contraction and recoil that enhance pump function of the heart, thus improve cardiac function and QoL.
This acute, interventional study is conducted in a single site, Renji Hospital, to evaluate the feasibility of diaphragm pacing and assess the beneficial effect of pacing-regulated diaphragm movement to the heart, with 10 cases of sample size and one-week follow-up after discharge.
Patients aged >=18 yrs;
Patients indicated for CRT or CRT-D , planned for LV lead implantation;
Patients are willing to participate in the study and provide signed informed consent
CRT or CRT-D replacement
Ischemic heart disease with CABG history
Diaphragm dysfunction history
Phrenic nerve injury