Feasibility Tests for Various Prism Configurations for Visual Field Loss

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-80
SponsorMassachusetts Eye and Ear Infirmary

About this trial

The investigators will develop and test different configurations of high-power prisms to expand the field of vision of patients with visual field loss to assist them with obstacle detection when walking. The study will involve multiple visits (typically four) to Schepens Eye Research Institute for fitting and testing with the prism glasses. The overall objective is to determine best designs and fitting parameters for implementation in prism devices for future clinical trials.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Visual field loss, either peripheral field loss or hemianopic field loss

Visual acuity of at least 20/50 in the better eye

In sufficiently good health to be able to complete sessions lasting 2-4 hours

Able to independently walk short distances

Disqualifiers

Any physical or mental impairments, including cognitive dysfunction, balance problems or other deficits that could impair the ability to walk or use the prism spectacles

A history of seizures in the last 6 months

Hemispatial neglect (subjects with hemianopic field loss only)

Trial design

Design model

Single group

Treatments tested in this trial

  • High power prisms

    Device

    High power prisms designed to shift images from blind areas into portions of the wearer's remaining, seeing, field of vision

Treatment groups

20 Participants
are divided into 1 treatment group
Group A: High power prismsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Field of view expansion

Horizontal and vertical extent of the expansion (in degrees) of the field of view

Time frame
Through study completion, an average of four months

Secondary outcomes

1

Pedestrian detection rate

Proportion of pedestrians detected (in simulated walking or simulated driving)

Time frame
Through study completion, an average of four months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Massachusetts Eye and Ear Infirmary

Lead sponsor

National Eye Institute (NEI)

Collaborator