Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-55
SponsorColumbia University

About this trial

The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal care or preconception care. The goal is to evaluate the acceptability of hereditary cancer testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention

Eligibility criteria

Qualifiers

Age: 18 years - 55 years

Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site

Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider

Patients with prior OCS but planned to repeat OCS are eligible

Disqualifiers

Patients who have previously completed a multigene hereditary cancer syndrome panel

Patients that have a hematologic cancer or hematologic pre-cancer

Patients who have a history of an autologous bone marrow transplant

Trial design

Treatments tested in this trial

  • Natera empower comprehensive hereditary cancer panel
  • Obstetrical carrier screening

Treatment groups

1,000 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Columbia University

Lead sponsor

Natera, Inc.

Collaborator