Fecal Microbiome Signature of Multi-Strain Probiotics Supplementation in Children and Adolescents With Inflammatory Bowel Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age5-18
SponsorInsel Gruppe AG, University Hospital Bern

About this trial

In this study the intestinal microbiome and metabolic profiles of patients with inflammatory bowel disease will be determined upon probiotic intervention.

Eligibility criteria

Qualifiers

Signed informed consent

Diagnosis of inflammatory bowel disease according to actual guidelines (Porto Criteria)

General good health

Ability to understand and follow study procedures and understand informed consent

Disqualifiers

Participation in other clinical studies interfering with study procedures.

Inability or contraindications to undergo the investigated intervention

Severe or acute flare of disease (for UC PUCAI score ≥35, for CD wPCDAI >40)

Treatment escalation within last 4 weeks for uncontrolled disease.

Trial design

Treatments tested in this trial

  • Probiotic Formula
  • Observation

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Insel Gruppe AG, University Hospital Bern

Lead sponsor

Clinical Trials Unit University of Bern

Collaborator

University of Bern

Collaborator