Fecal Microbiota Transplantation for Radiation Enteritis
ConditionRadiation Enteritis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorThe Second Hospital of Nanjing Medical University
About this trial
Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for radiation enteritis.
Eligibility criteria
Qualifiers
age ≥18 years old;
Radiation enteritis diagnosed by colonoscopy after finishing radiotherapy.
Disqualifiers
Patients who were pregnant or nursing;
Patients who were unable or unwilling to undergo a gastroscopy;
Patients who had gastrointestinal infection;
Patients with cardiopulmonary failure.
Trial design
Treatments tested in this trial
- Fecal Microbiota Transplantation (FMT)
Treatment groups
70 Participants
are divided into 2 treatment groupsSponsors and collaborators
The Second Hospital of Nanjing Medical University
Lead sponsor
Jiangxi Provincial Cancer Hospital
Collaborator
Source ClinicalTrials.gov