Feedback Loop Between Intracranial Atherosclerosis and Cerebral Small Vessel Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30+
SponsorChinese PLA General Hospital
The present study aims at verifying the mutual effects between intracranial large artery atherosclerosis and cerebral small vessel disease on disease progression and prognosis by magnetic resonance imaging, and providing biomarkers for the early prevention and treatment of cerebrovascular disease.
Age ≥ 18 years
At least one intracranial artery ≥ 50% atherosclerotic stenosis
Modified Rankin Scale < 2
Mini-mental State Examination > 24
Concurrent ipsilateral extracranial artery ≥ 50% stenosis
Pregnant women
Contraindications to magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies)