Feedback Loop Between Intracranial Atherosclerosis and Cerebral Small Vessel Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30+
SponsorChinese PLA General Hospital

About this trial

The present study aims at verifying the mutual effects between intracranial large artery atherosclerosis and cerebral small vessel disease on disease progression and prognosis by magnetic resonance imaging, and providing biomarkers for the early prevention and treatment of cerebrovascular disease.

Eligibility criteria

Qualifiers

Age ≥ 18 years

At least one intracranial artery ≥ 50% atherosclerotic stenosis

Modified Rankin Scale < 2

Mini-mental State Examination > 24

Disqualifiers

Concurrent ipsilateral extracranial artery ≥ 50% stenosis

Pregnant women

Contraindications to magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies)

Trial design

Treatments tested in this trial

  • Magnetic resonance imaging

Treatment groups

300 Participants
are divided into 1 treatment group

Sponsors and collaborators