Femoral BMD Change Following Cemented or Cementless Total Knee Arthroplasty
ConditionKnee Arthropathy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age55+
SponsorUniversity of Wisconsin, Madison
About this trial
The purpose of this study is to examine femur bone mineral density (BMD) change before and after surgery in patients receiving cemented or cementless total knee arthroplasty (TKA). performed with manual or robotic methods. 100 participants will be enrolled and can expect to be on study for up to 26 months.
Eligibility criteria
Qualifiers
Patients age greater than or equal to 55 years undergoing TKA with no prior total joint arthroplasty on the surgical side
Normal BMD or osteopenia with Fracture Risk Assessment Tool (FRAX) not meeting Bone Health and Osteoporosis Foundation (BHOF) treatment recommendations, i.e., 10-year major osteoporotic fracture risk greater then or equal to 20 percent or hip fracture risk greater than or equal to 3 percent.
Disqualifiers
Hip or spine T-score less than or equal to -2.5
History of low trauma fracture after age 50
FRAX fracture risk calculation greater than or equal to 20 percent for major osteoporotic fracture or greater than or equal to 3 percent for hip fracture
Prior or current use of osteoporosis medications
Trial design
Treatments tested in this trial
- Cement
- Cementless
- Manual Surgery
- Robotic Surgery
Treatment groups
100 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov