Fertility Sparing Management of EndomeTrial Cancer and Hyperplasia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age19-39
SponsorVancouver Coastal Health Research Institute
About this trial
This study protocol evaluates the use of hysteroscopic endomyometrial resection in women diagnosed with atypical endometrial hyperplasia or grade I endometrial cancer who have not responded to anti-hormone therapy. Patients in this study wish to preserve fertility.
Eligibility criteria
Qualifiers
Age less than 40 years
Grade I endometrial endometrioid adrenocarcinoma (EC) with less than 1/3 of the endometrial surface involved.
Atypical endometrial hyperplasia (AH)
MRI demonstrating less than 1/3 myometrial invasion if the patient has EC
Disqualifiers
Age 40 years and over
Grade 2 or 3 endometrioid endometrial adenocarcinoma or non-endometrioid pathology
Greater than 1/3 involvement of the endometrial surface in patients with Grade I EC
Women who are not able to provide informed consent
Trial design
Treatments tested in this trial
- Hysteroscopic uterine resection
Treatment groups
30 Participants
are divided into 1 treatment groupSponsors and collaborators
Vancouver Coastal Health Research Institute
Lead sponsor
University of British Columbia
Collaborator
Source ClinicalTrials.gov