The goal of this clinical trial is to explore the feasibility and outcome of fertility-sparing therapy in Stage IA G1-G2 Endometrial Cancer with less than 1/2 myometrial invasion. Researchers will render participants indication-extended fertility-sparing therapy. Researchers will compare the myometrial invasion group with the no myometrial invasion group to see if it is possible to propose an extension indication of fertility-sparing therapy for endometrial cancer.
Stage IA (FIGO 2009) ;
Pathological diagnosis: endometrial adenocarcinoma G1-G2;
MRI or ultrasound: tumor limited to endometrium or invading less than 1/2 of myometrium；
18 years old ≤ Age ≤ 45 years old;
Complicated with any other malignancy；
Contraindications to conservative treatment；
Contraindications to progestin use;
Contraindications to pregnancy, or judged by the researcher to be unfit for pregnancy or delivery.
Peking University People's Hospital
Lead sponsor
Peking University Third Hospital
Collaborator
Peking Union Medical College Hospital
Collaborator
Third Military Medical University
Collaborator
Tianjin Medical University General Hospital
Collaborator
Tongji Hospital
Collaborator
Qilu Hospital of Shandong University
Collaborator
Shengjing Hospital
Collaborator
Beijing Chao Yang Hospital
Collaborator
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Collaborator