Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorAnkara City Hospital Bilkent

About this trial

Longitudinal meniscal tears are a type of meniscal injury characterized by a displaced fragment of the meniscus that flips over into the joint, often resembling a buckle or handle. These tears typically occur in the medial meniscus and are often associated with traumatic knee injuries, particularly in athletes.

The displaced meniscal fragment can cause mechanical symptoms such as locking, clicking, or catching of the knee, as well as pain and swelling. If not properly treated, buckle-handle meniscal tears can lead to further complications, including chronic knee instability, increased risk of osteoarthritis, and persistent joint pain.Repairing a longitudinal meniscal tear offers several advantages over partial meniscectomy, particularly in preserving knee function and preventing long-term complications.

Meniscal repair aims to restore the integrity of the meniscus, which plays a crucial role in load distribution, shock absorption, and joint stability.

Utilizing a fibrin clot during the repair of a buckle-handle meniscal tear can enhance the healing process and improve surgical outcomes. Fibrin clots act as a biological scaffold, promoting tissue regeneration by providing a matrix that facilitates cellular migration and proliferation.

The purpose of this study was to compare longitudinal meniscal tear repair reinforced with fibrin clot with routine end-to-end repair in a prospective randomized controlled trial.

Eligibility criteria

Qualifiers

Presenting with a painful meniscus (lateral or medial) longitudinal tear

Being between the ages of 18 and 50

Not having undergone surgery on the same knee before

Having an MRI taken at the end of the 1st year post-surgery

Disqualifiers

Having additional collateral ligamentous damage along with the meniscus tear (such as MCL or LCL)

Incomplete clinical scores at the end of the study

A history of previous surgery on the same knee

Having an active infection

Trial design

Treatments tested in this trial

  • Fibrine Clot-augmented Meniscal Repair
  • Conventional Meniscal Repair

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Ankara City Hospital Bilkent

Lead sponsor

Ankara Etlik City Hospital

Collaborator