Finger Plethysmography to Predict Fluid Responsiveness in Healthy Pregnancy and Severe Preeclampsia
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorStanford University
About this trial
The goal of this observational study is to determine whether noninvasive finger plethysmographic cardiac output monitoring can help predict fluid responsiveness in pregnant women, including those with preeclampsia with severe features.
The main questions it aims to answer are :
* Can changes in cardiac output measured by finger plethysmography predict fluid responsiveness? * How does this method perform compared with standard echocardiographic assessment? Participants will provide consent and undergo noninvasive hemodynamic monitoring and a brief reversible physiological challenge.
Eligibility criteria
Qualifiers
Women diagnosed with preeclampsia with severe features following ACOG recommendations (systolic/diastolic BP >160/110 mmHg, proteinuria, or other severe features like headaches, visual disturbances, kidney/liver impairment, thrombocytopenia).
Healthy pregnant women at term (for comparison group, e.g., scheduled for elective Cesarean delivery).
Disqualifiers
Patients who can not provide written consent to participate in the study
BMI greater than 40 kg/m²
Multiple pregnancy (twins, triplets, etc.)
Non-reassuring fetal heart tracing
Trial design
Treatments tested in this trial
- Noninvasive finger plethysmographic cardiac output monitoring
- Standard transthoracic echocardiographic assessment
Treatment groups
88 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov