About this trial
Non randomized study with two groups. The study group includes patients with suspected malignant pleural effusion, in whom the investigation of pleural effusion begins directly with pleural biopsy by Local Anesthesia Thoracoscopy (LAT).
The Control Group includes patients who come to the same hospital and are treated with the Standard of Care (SOC) strategies were used. Efficacy of LAT, Sensitivity, Hospitalization, time to diagnosis and general safety and comfort of the groups' subjects will be assessed.
Eligibility criteria
Qualifiers
Undiagnosed pleural effusion with the character of a lymphocytic exudate
Disqualifiers
Empyema
Transudate pleural effusion.
Central airway obstruction by tumor.
Existence of extensive adhesions that do not allow the development of iatrogenic pneumothorax and the safe entry of the thoracoscope.
Trial design
Treatments tested in this trial
- Local Anesthesia Thoracoscopy
- Pleuroscopy with Rigid Thoracoscope and Forceps biopsies
Treatment groups
Sponsors and collaborators
National and Kapodistrian University of Athens
Lead sponsor
Sotiria Thoracic Diseases Hospital of Athens
Collaborator