Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAnkara Etlik City Hospital
About this trial
This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc herniation surgery under general anesthesia.
Adult patients aged 18-65 years, with ASA physical status I-III and a body mass index of 18-30 kg/m², will be allocated to receive either FCV or VCV during routine intraoperative mechanical ventilation. Ventilatory parameters, including peak airway pressure, plateau pressure, pulmonary compliance, EtCO₂, SpO₂, and arterial blood gas variables, will be recorded at predefined time points after intubation.
The primary endpoint is the PaO₂ value measured after 20 minutes in the prone position.
By comparing respiratory mechanics and oxygenation between the two ventilation modes, this study aims to contribute to the optimization of intraoperative ventilatory management in lumbar disc herniation surgery.
Eligibility criteria
Qualifiers
Age between 18 and 65 years
ASA physical status I-III
Body Mass Index between 18 and 30 kg/m²
Disqualifiers
Age < 18 years or > 65 years
Known or previously diagnosed pulmonary disease
Patients with severe preoperative pulmonary function impairment (e.g., FEV₁ < 50% predicted, severe restrictive or obstructive pathology)
Patients with markedly altered lung anatomy or function due to prior major thoracic surgery
Trial design
Treatments tested in this trial
- FCV Group
- VCV Group
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov